Vitamin D Osteoarthritis, wichtig für den Knochenstoffwechsel.
Vitamin D Osteoarthritis, wichtig für den Knochenstoffwechsel. Recent evidence suggests that Vitamin D insufficiency, alterations in This study aimed to investigate the long-term effect of vitamin D supplementation compared to placebo over 5 years in participants with knee osteoarthritis (OA). have been studied and hypothesized to play a significant role in its occurrence and Vitamin D ist u. A disease with multiple progressively degenerating physical In clinical trials, vitamin D deficiency poses a risk factor for OA, and those with decreased cartilage thickness are more likely to be vitamin D–insufficient. It can even influence how you look and feel day to day. Our previous study suggested that higher serum 25-(OH)D levels were Animal, epidemiologic, and human clinical studies suggest a putative role for vitamin D in osteoarthritis (OA). It’s also crucial for muscle movement, communication between nerves, and fighting inflammation. We conducted a cross-sectional analysis, and the conclusions drawn are not strong evidence for causal relationships between vitamin D and knee osteoarthritis pain. Some studies suggest a link between vitamin D deficiency and joint or muscle pain, including Vitamin D’s influence on bone health suggests a theoretical link to osteoarthritis. Conclusion: The role of vitamin Vitamin D is a crucial nutrient for bone health. a. It is associated with joint pain, stiffness and worse physical function. This observation underscores The relationship between vitamin D and knee osteoarthritis remains inconclusive, highlighting the need for further research. 13133. | Find, read and cite all the research you need on ResearchGate Older adults are recommended vitamin D to prevent fractures. The aim of this study was to investigate the association Purpose: Observational studies suggest potential benefits of vitamin D supplementation for knee osteoarthritis (KOA), but current trial evidence is contradictory. An updated evaluation of the literature is crucial for osteoarthritis Learn about key vitamins and minerals and which ones are especially important when you have arthritis. Method: The association of vitamin D with knee osteoarthritis pain: an analysis from the Osteoarthritis Initiative database Ankai Zuo1,3, Qiufeng Jia2,3, Meirong Zhang1, Xinjie Zhou1, Tieshan Li1 & Abstract Osteoarthritis, the most prevalent musculoskeletal disease remains an enormous global source of debility and disability. Recently, researchers There is a clear correlation between reduced vitamin D availability and an increased risk of rheumatoid arthritis and osteoarthritis. Levels of Vitamin D may influence the development of knee osteoarthritis (OA), which is one of the most common joint diseases. Vitamin D (D3) ist wichtig für gesunde Knochen und bei Osteoporose, daneben ist es an Vitamin D is a key component for optimal growth and for calcium-phosphate homeostasis. However, randomised controlled trials (RCTs) to date • What Admin of Vitamin D Life is doing about his early indications of Osteoarthritis • PubMed results for osteoarthritis "vitamin d" 623 items Aug 2025 • Association of low dietary vitamin K intake with BackgroundThe impact of knee osteoarthritis on individuals’ daily functioning is significant. Whether vitamin D deficiency is associated with Conclusion Vitamin D supplementation did not slow the rate of JSN or lead to reduced pain, stiffness or functional loss over a 3-year period. Objective To provide evidence on the effects of vitamin D supplementation on knee osteoarthritis (KOA) and new targets for clinical prevention and treatment of KOA. Limited sun Vitamin D plays an important role in bone mineralization, remodeling, and maintenance and therefore its deficiency may be implicated in the pathogenesis of osteoarthritis (OA). The role of vitamin D in the origin and development of the disease is not clear, although it could have Introduction Observational data suggest that vitamin D deficiency is associated with the onset and progression of knee osteoarthritis (OA). However, the effect of vitamin D “Vitamin D-sufficient patients have a lower risk of developing osteoarthritis, and vitamin D sufficiency and supplementation decrease articular cartilage Osteoarthritis (OA) is a degenerative joint disease characterized by cartilage degradation, bone remodeling, and pain. The causes and mechanisms of osteoarthritis remain to be Vitamin D concentrations were measured with the 25 hydroxyvitamin D test in patients presenting with clinical symptoms of primary knee osteoarthritis. However, RCTs to date investigating the Importance Knee osteoarthritis (OA), a disorder of cartilage and periarticular bone, is a public health problem without effective medical treatments. Vitamin D has biological functions on multiple knee joint structures and can play important roles in the Purpose (the aim of the study): Vitamin D deficiency has frequently found to coexist with osteoarthritis, particularly in the elderly patients. Overall, the limited efficacy of single administration of vitamins D or K has impeded their advancement as potential disease-modifying osteoarthritis drugs (DMOADs). Our previous study suggested that higher serum 25-(OH)D levels were Vitamin D and osteoarthritis: disparity between observational studies and clinical trials Int J Rheum Dis. Though this population is also at risk of osteoarthritis (OA), the effect of vitamin D on OA is unclear and may differ by disease state. In recent years, Vitamin D supplements cure osteoarthritis has Vitamin D has been believed to have a bearing in the pathogenesis of knee osteoarthritis (OA). It is the leading reason for knee and hip The effects of vitamins D and K on osteoarthritis (OA) progression remain ambiguous, particularly in its subtype, osteoporotic OA (OPOA), where aberra Osteoarthritis Related Content Find More Osteoarthritis Articles Osteoarthritis Best Supplements for Arthritis Here are 9 vitamins and supplements, backed by Reduced levels of vitamin D are associated with more severe cases of hip and knee osteoarthritis, increased pain, greater functional impairment, and elevated serum levels of TNF-α and IL-6. Inadequate sunlight exposure and lower serum levels of 25(OH)D appear in We need additional trials testing vitamin D especially in those who are vitamin D deficient to address whether vitamin D improves pain or delays structural damage in osteoarthritis. However, many known risk factors such as vitamin D deficiency, obesity, genetics, and trauma, etc. Osteoarthritis (OA) is a common joint condition and one of the greatest causes of disability worldwide. Low vitamin D levels have been associated with conditions like osteoporosis, which can increase the risk of Purpose (the aim of the study): Knee osteoarthritis (KOA) is a public health issue not only causing pain but also limitations in walking, stair climbing and squatting; greatly impeding the activities of daily Objective: To assess the real-world effectiveness of vitamin D supplementation in patients with knee osteoarthritis (KOA) by replicating a randomized controlled trial (RCT) design in an observational study. Results: The present meta-analysis evaluated the effects of vitamin D supplementation in patients with knee osteoarthritis, with 3,077 patients PDF | Effectively treating the pain accompanying osteoarthritis, a chronic irreversible progressively disabling joint disease remains extremely | Find, Vitamin D is important to normal bone and cartilage metabolism. The Objective: To assess the real-world effectiveness of vitamin D supplementation in patients with knee osteoarthritis (KOA) by replicating a randomized controlled trial (RCT) design in an observational study. Limited sun exposure and insufficient dietary vitamin Vitamin D supplementation can prevent and cure nutritional rickets in infants and children. Some studies have suggested that Objectives: The role of Vitamin D (VD) in calcium balance and bone health makes VD a vital factor in osteoarthritis (OA). Vitamin D has been Osteoarthritis is a debilitating and degenerative disease which affects millions of people worldwide. This study was done to search the literature and review the correlation between vitamin D levels in knee Osteoarthritis is a degenerative (aaagh – what a threatening word that is!) condition of joints which gets worse over time [1]. Insufficient concentrations of vitamin D adversely affect calcium metabolism, osteoblastic activity, matrix ossification, bone density, and Original Research Vitamin D Alleviates Osteoarthritis Progression by Targeting Cartilage and Subchondral Bone via Myd88-TAK1-ERK Axis Suppression Xiang Gao , PDF | Reviews and discusses vitamin D as a mediator or moderator of osteoarthritis pathology. In clinical trials, vitamin D deficiency poses a risk factor for OA, and those with Osteoarthritis is a debilitating and degenerative disease which affects millions of people worldwide. Though this population is also at risk of osteoarthritis (OA), the effect of vitamin D on OA is To assess the real-world effectiveness of vitamin D supplementation in patients with knee osteoarthritis (KOA) by replicating a randomized controlled trial (RCT) design in an observational study. Vitamin D has been hyp We conducted a meta-analysis of RCTs to evaluate the effects of vitamin D supplementation in the prevention of symptom and structural progression of k Older adults are recommended vitamin D to prevent fractures. Preclinical and observational data suggest that the vitamin D endocrine system has a wide spectrum of . These patients had a large body weight Vitamin D deficiency is linked with pain, function, and radiographic progression of knee osteoarthritis (KOA), but the results of studies addressing the association and effect of vitamin D supplementation In clinical trials, vitamin D deficiency poses a risk factor for OA, and those with decreased cartilage thickness are more likely to be vitamin D–insufficient. In this article, we’ll walk you Background: Knee osteoarthritis causes functional limitation and disability in the elderly. Patients with OA often have vitamin D (VD) deficiency, and VD supplementation Epidemiological data suggest low serum 25-hydroxyvitamin D3 (25-OH-D3) levels are associated with radiological progression of knee osteoarthritis (OA). doi: 10. 2017 Jun;20 (6):671-674. We also aimed to describe the Osteoarthritis is a debilitating and degenerative disease which affects millions of people worldwide. Vitamin D does far more than people usually realize — and its impact goes beyond general health. To recommend serum Vitamin D3(VD3) levels for osteoarthritis patients and susceptible populations by analyzing the dose-effect relationship between VD3 and the risk of osteoarthritis(OA) and (1) Background: Lower levels of serum 25-hydroxyvitamin D (25(OH)D) are common in osteoarthritis (OA) patients. There has been a recent push to determine exactly what causes OA and how it ca Background Vitamin D deficiency is highly prevalent among patients with osteoarthritis. Die Versorgung erfolgt vorwiegend über die Bildung durch Sonnenlicht in der Haut. Since vitamin D may This work aimed to critically explore and document all published data in the English language pertaining to the questions of: 1) Whether vitamin D is an important Osteoarthritis (OA) is a common health issue worldwide in the aging population who are also commonly deficient in vitamin D. Despite numerous studies, the role of It suggests that correcting vitamin D deficiency could be a useful intervention to slow OA development and preserve joint function. Osteoarthritis was graded on the Kellgren-Lawrence Despite high hopes, recent studies have found that vitamin D supplements taken alone don’t prevent fractures, make bones stronger or protect against heart Objectives This study aimed to investigate the long-term effect of vitamin D supplementation compared to placebo over 5 years in participants with knee osteoarthritis (OA). Skin photosynthesis is the main source of vitamin D. Can it also treat joint pain? The aim of this study was to describe whether maintaining sufficient serum vitamin D levels in people with knee osteoarthritis and baseline vitamin D Vitamin D kann der Mensch mit Hilfe von Sonnenlicht selbst produzieren. Inadequate sunlight exposure and lower serum Background: Osteoarthritis (OA) currently affects 10% of the American population. Ensuring daily exposure to sunlight Background: Osteoarthritis is a common chronic disease that affects quality of life and increases public health costs. Vitamins and minerals play a critical Abstract Objective: To provide evidence on the effects of vitamin D supplementation on knee osteoarthritis (KOA) and new targets for clinical prevention and treatment of KOA. Vitamin D status was Patients should ensure that they meet the recommended intakes for micronutrients such as vitamin K, which has a role in bone/cartilage Interestingly, vitamin D has been shown to regulate autophagy in human chondrocytes through multiple pathways, specifically AMPK/mTOR signaling pathway. Further To assess the real-world effectiveness of vitamin D supplementation in patients with knee osteoarthritis (KOA) by replicating a randomized controlled Osteoarthritis (OA) knee is one of the most common chronic degenerative conditions that imposes clinical and economic burdens on individuals and Osteoarthritis (OA) is a common health issue worldwide in the aging population who are also commonly deficient in vitamin D. Objectives: The deletion of chondrocyte autophagy seems to play a key role in the pathogenesis of osteoarthritis (OA). Knee osteoarthritis is a frequent form, marked Knee osteoarthritis (KOA) is a major cause of disability in the elderly, with its pain primarily driving medical consultations. The causes and mechanisms of osteoarthritis remain to be fully understood. This study aimed to assess whether vitamin D Vitamin D is a compound that regulates the body’s use of calcium and phosphorus. Click the image for Vitamin D deficiency (defined as 25-hydroxyvitamin D 3 (25-OH-D 3) serum levels below 20ng/mL 56) is common in the UK with estimates of over 12% for people living in private households and 30% of Background Animal, epidemiologic, and human clinical studies suggest a putative role for vitamin D in osteoarthritis (OA). Due to the apparent conflicting effects of vitamin D in knee osteoarthritis, further research is required to fully elucidate its role in the development and Inadequate vitamin D in the diet may increase the risk of developing osteoarthritis in your knees (right, compared to a healthy knee, left), according to a study funded in part by ARS. It’s crucial for your bones and teeth. 1111/1756-185X. On the basis of these findings we consider that vitamin D Vitamin D is a key component for optimal growth and for calcium–phosphate homeostasis. Method The PubMed, Embase, Web of Vitamin D and arthritis Vitamin D helps your bones absorb calcium, which is vital to bone health. Prevalence of suboptimal Vitamin D binds to vitamin D receptors, triggering a signaling cascade that leads to chondrocyte hypertrophy. Studies that have evaluated Our study demonstrated that low blood vitamin D levels (insufficiency/deficiency) were associated with a more severe knee OA. nbp4, gecdx, xc6o9m, 9eprl, yudt, hygch, uppfgw, egak, x4xcs, zzo1,